Centrilobular Nodules with Tree-in-Bud Pattern

Axial CT image shows multiple micronodules in the left lung. Most are not subpleural. They are non-uniform and there are some that have V- or Y shape.

Facts: Centrilobular Nodules

• Nodules limited to centrilobular structure (central core), sparing pleural surfaces
• Most peripheral nodules are centered 5-10 mm from fissures or pleural surface
• Evenly distribulted
• Common cause: without tree-in-bud - infection, inflammation, hypersensitivity, vascular disease
• Common cause: with tree-in-bud - infection