Fig. Axial CT of the chest shows diffuse bilateral ground-glass opacities superimposed by interlobular septal thickening (arrowheads) and intralobular lines (blue arrows). Note a left chest tube used to treat left pneumothorax, which brought this patient to the hospital.
- Ground-glass opacity superimposed with interlobular septal thickening and intralobular lines
- Can be scattered or diffuse
- Can be caused by alveolar filling process, interstitial process, or a combination
- CLASSIC: Pulmonary alveolar proteinosis
- COMMON: Pneumocystis jirovecii pneumonia (PCP), pulmonary edema (ARDS), pulmonary hemorrhage
- NOT COMMON: Bronchioloalveolar carcinoma, alveolar sarcoidosis, nonspecific interstitial pneumonitis (NSIP), Cryptogenic organizing pneumonia (COP), lipoid pneumonia