- Lymphoma accounts for 0.2% - 1.2% of all colon malignancies
- Most common form of GI tract lymphoma is non-Hodgkin lymphoma (NHL)
- Most common sites of GI tract lymphoma is stomach, followed by small bowel
- For colonic lymphoma, most common site is cecum
- Nonspecific clinical signs and symptoms
- Due to rarity, Rx is not standardized. Often, it is surgically resected then chemotherapy is given
CT patterns of GI tract lymphoma:
- Nodular thickening of bowel wall
- Discrete polyp (causing intussusception)
- Long, distensible infiltrative lesion with ill-defined, thick walls with aneurysmal dilatation of the lumen
- Large exoenteric mass extending into adjacent soft tissues
Features differentiating lymphoma from adenocarcinoma of GI tract
- Bulky lymphadenopathy (lymphoma more likely)
- Marked luminal dilatation of bowel segment that is involved (lymphoma more likely)
Our case: Colonic mucosa-associated lymphoid tissue (MALT) lymphoma in a 67-year-old man.
Buckley JA, Fishman EK. CT evaluation of small bowel neoplasms: spectrum of disease. Radiographics 1998;18:379.
Bairey O, et al. Non-Hodgkin lymphomas of the colon. Hematol 2006;8:832.