September 6, 2010

Mesoblastic Nephroma

A 10-day-old infant presented with hematuria. Multiple CT images show a large heterogeneous mass originating from the lower pole of the right kidney (cortical beak sign noted, pink arrow). The mass extends into the right renal pelvis and causes mild hydronephrosis.

  • Synonyms: mesoblastic nephroma, leiomyomatous hamartoma, mesenchymal hamartoma, renal fibroma, Bolande tumor.
  • It is the most common solid renal tumor in the newborn.
  • This tumor is believed to arise from metanephric blastema or secondary mesenchyme.
  • Patients usually presents with a palpable flank mass.
  • Prognosis is excellent with nephrectomy and wide resection
Imaging Findings
  • Large solid intrarenal mass, which typically involves or extends to the renal sinus.
  • Hemorrhage, necrosis or cystic portions are uncommon.
Table: Age Presentation of Renal Tumors in Children


1. Donnelly LF. Diagnostic imaging pediatrics. Amirsys. Manitoba. 2005.
2. Lowe LH, Isuani BH, Heller RM, Stein SM, Johnson JE, Navarro OM, Hernanz-Schulman M. Pediatric renal masses: Wilms tumor and beyond. Pediatric renal masses: Wilms tumor and beyond. Radiographics. 2000; 20:1585-603.

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