February 18, 2010

Multiple Well-Defined Soft-Tissue Opacities in the Breasts

Mediolateral oblique mammogram of both breasts show multiple, innumerable, well-defined soft-tissue opacities (arrows) and enlarged nipples in a 40-year-old woman.

Differential Diagnosis
  • Cysts
  • Fibroadenomas: 10-20% are multiple
  • Skin lesions: such as neurofibromas
  • Intramammary lymph nodes
  • Metastasis: melanoma (most common), lymphoma (2nd most common), lung, ovary, soft tissue sarcoma (breast metastasis has a very poor prognosis)
Our case: neurofibromatosis

Davies SG. Chapman & Nakielny's Aids to radiological differential diagnosis, fifth edition, 2009.

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