March 1, 2013

Gallbladder Cholesterolosis

Longitudinal US image of the gallbladder demonstrates multiple tiny echogenic spots within the wall with comet-tail artifacts. No evidence of gallbladder wall thickening. 


  • Other names: cholesteatosis, strawberry gallbladder
  • Common, degenerative, proliferative changes of gallbladder
  • Usually in females during their 4th and 5th decades
  • Usually asymptomatic
  • Not associated with increased risk of malignancy, cholelithiasis or cholecystitis
Differentiation from Adenomyomatosis:
  • May be difficult at times because they may coexist and are believed to be a continuum of same pathology
  • In cholesterolosis, the gallbladder has normal size, shape, lumen and often normal wall thickness

Schmidt G. Differential diagnosis in  ultrasound imaging: A teaching file, 2006

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