April 12, 2010

Calcified Lung Masses

Fig. 1: Chest radiograph of a 24-year-old man shows a dense retrocardiac opacity and a dense nodule in the right lower lobe (arrows).
Fig. 2: Axial CT image confirms the presence of multiple nodules in the lungs (arrows). The nodules/masses have a soft tissue component and are partially calcified. They are predominantly in the lower lung zones.


Differential Diagnosis:
  • Calcified/ossified metastasis: osteosarcoma, chondrosarcoma, mucinous adenocarcinoma of colon or breast, papillary carcinoma of thyroid, cystadenocarcinoma of ovary and carcinoid
  • Infections: tuberculosis, histoplasmosis
  • Treated neoplasm: lymphoma following radiotherapy
Our case: calcified/ossified metastases from osteosarcoma

Reference:
Davies SG. Chapman & Nakielny's Aids to Radiological Differential Diagnosis, 5th edition, 2009.

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