

Lung Abscess
- Localized suppuration with destruction of lung parenchyma
- Round, thick-walled cavity in areas of destroyed lung
- Typically irregular wall, irregular luminal margin and exterior surfaces
- Usually treated by prolonged antibiotics and postural drainage
Empyema
- Pus in the pleural cavity
- "Split pleural" sign: separation of uniformly thickened visceral pleura from parietal pleura
- Compression of uninvolved lung
- Usually require early tube drainage
Differentiating the Two
- Most specific signs: "split pleura" sign of empyema, compression of adjacent uninvolved lung in empyema
- Helpful signs: at least one wall of empyema is thin, uniform and smooth on both luminal margin and exterior surface
- Less reliable sign: size, shape (oval vs round), chest wall angle (obtuse vs acute)
Reference:
Stark DD, Federle MP, Goodman PC, et al. Differentiating lung abscess and empyema: radiography and computed tomography. AJR 1983;141:163-167.
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Excellent post....usmleworld doesn't do a very good job explaining the differences between an empyema and a pulmonary abscess.
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